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Karmanos, WSU SOM scientists receive Strategic Research Initiative Grants for promising research

The Barbara Ann Karmanos Cancer Institute has announced the winners of its 2012 Strategic Research Initiative Grants, which fund innovative intra- and inter-programmatic projects, which exhibit great potential in leading to multi-investigator grants.
 
A total of six grants have been given to researchers, including three $50,000 grants and three $100,000 grants. These grants last for one year.

Winners of the $50,000 grants include:

   
Felicity Harper, Ph.D., assistant professor in the Department of Oncology and Population Studies and Disparities Research at Karmanos and Wayne State University School of Medicine (WSU SOM) for her project, “Communication about Lung Cancer Risk and Lung Cancer Prevention Behavior in High-Risk Families.” 
 
Sandeep Mittal, M.D., co-leader of the Neuro-oncology Multidisciplinary Team at Karmanos for the project, “Histopathologic and molecular correlates of kynurenine pathway and aryl hydrocarbon reception activation in primary gliomas and metastatic brain tumors.”  
 
   
Csaba Juhasz M.D., Ph.D., associate professor of Pediatrics and Neurology at WSU SOM for the project, “Histopathologic and molecular correlates of kynurenine pathway and aryl hydrocarbon reception activation in primary gliomas and metastatic brain tumors.”  
 
Rouba Ali-Fehmi, M.D., assistant professor in the Department of Pathology at Karmanos and WSU SOM for her project “15-LOX ½ as a novel Putative Tumor Suppressor and Potential Prognostic and Therapeutic Marker in Ovarian Cancer.” 
 

Winners of the $100,000 grants include:


   
David Gorski, M.D., Ph.D., associate professor and co-medical director of the Walt Comprehensive Breast Center at Karmanos and WSU SOM and Bonnie Sloane, Ph.D., distinguished professor of Pharmacology at WSU SOM for their project, “MicroRNA-130a: A potential biomarker and target in triple negative breast cancer.”  
 
Zenquan Yang, assistant professor in the Department of Oncology and Breast Cancer Biology at Karmanos and WSU SOM, and Olivia Merkel, Ph.D., assistant professor in the Department of Pharmaceutical Sciences at WSU SOM for “Nanoparticle delivery of siRNA targeting the oncogenic histone modifying enzyme GASC1 in breast cancer.” 
 
   
Gilda Hillman, Ph.D., associate professor of Radiation Oncology at Karmanos and WSU SOM, for  “Targeting Tumor-Associated Macrophages with PLX3397 to Enhance Radiotherapy of Prostate Cancer.”  
 
Izabela Podgorski, Ph.D., assistant professor in the Department of Pharmacology at Karmanos and WSU SOM,for “Targeting Tumor-Associated Macrophages with PLX3397 to Enhance Radiotherapy of Prostate Cancer.”  
 

 
 
Elisabeth Heath, M.D., member of the Genitourinary Multidisciplinary Team and associate professor in the Department of Oncology at Karmanos and WSU SOM, for “Targeting Tumor-Associated Macrophages with PLX3397 to Enhance Radiotherapy of Prostate Cancer.”  
 
 

“These projects exemplify the outstanding work that is being conducted each day at Karmanos Cancer Institute and Wayne State University School of Medicine,” said Gerold Bepler, M.D., Ph.D., president and CEO of Karmanos. “It’s just this sort of dynamic and collaborative research that leads to the cancer therapies of tomorrow and makes Karmanos, in partnership with WSU SOM, one of the international leaders in cancer research.

“Congratulations to all the investigators who have received these grants.”
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