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Volunteers Needed for Karmanos’ INHALE Study

Doctors know that about 15 percent of smokers develop lung cancer. They also know that patients with Chronic Obstructive Pulmonary Disease (COPD) — also known as chronic bronchitis and emphysema — are at increased risk of developing lung cancer, even if they never smoked. What isn’t well understood are the connections between smoking, COPD and lung cancer.

To learn more about the factors that cause lung disease, researchers at the Karmanos Cancer Institute, Wayne State University School of Medicine and Henry Ford Health System are studying the genetics of lung inflammation. The National Cancer Institute is funding the study, INHALE (Inflammation, Health and Lung Epidemiology), with a five-year, $9 million grant aimed at identifying genetic and environmental determinants of lung disease.

More than 4,000 current and former smokers (with and without lung disease) will participate in the recently launched INHALE study. 

“This is the first study to compare the genetics of inflammation in patients with lung cancer, patients with COPD, and smokers with neither disease to develop a genetic risk profile. The profile can be used to develop screening guidelines moving forward,” says Ann G. Schwartz, Ph. D., MPH, Karmanos deputy center director and executive vice president for Research and Academic Affairs. Dr. Schwartz is the principal investigator of the study.

With your help, we hope to learn why some people develop lung health problems while others do not.

Eligible participants:

  • Between 40-89 years old
  • Current or former (quit within 25 years) smoker
  • No previous cancer diagnosis
  • Have health insurance (includes Medicaid or Medicare) 

Participation includes:

  • 30-60 minute interview
  • Donation of saliva and blood samples
  • Lung screening exams (spirometry & chest CT)
  • Compensation for your time

For more information or to enroll in the study, call 1.866.828.2339 (toll-free) 

© 2014 Karmanos Cancer Institute Pencil
The Barbara Ann Karmanos Cancer Center is accredited by The Joint Commission.
If members of the public have any quality-of-care or safety concerns, they may notify The Joint Commission at 630-792-5800.