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Phase 1 Clinical Trials Program

The Phase I Program at Karmanos is focused on developing new therapies and drugs to fight cancer. It is one of just 14 National Cancer Institute-funded Phase I programs in the country, and the only one of its kind in Michigan. Many of the clinical trials offered have been developed by our own physicians and researchers. Learn more about clinical trials and how they help cancer patients. 

Program Mission

To offer hope and longer life to patients with all types of cancer by making available the newest types of therapy, by creating new knowledge about how these therapies fight cancer and by providing national leadership in testing these new therapies.

What is a Phase I Clinical Trial?

A typical Phase I clinical trial evaluates how a new drug should be given, either orally or injected into the blood, how often and what dosage is safe. A Phase I trial is often the first time a drug has been given to human, or the first time a new drug has been given to a human in combination with another standard cancer treatment. Because we are working with new drugs, most Phase I trials only enroll a small number of patients.

Phase I clinical trials provide the initial pieces of critical information about the effect of a new drug on humans which is necessary for future clinical development. Once the initial Phase I trial is complete, drug development may progress into larger clinical studies that continue to test the safety of the new drug and how well it works in treating a particular type of cancer.

The Phase I Team meets with and treats patients at the state-of-the-art Eisenberg Center for Translational Therapeutics, located at the Karmanos Cancer Center’s midtown Detroit campus.

Make a Donation

For patients with advanced cancer who have exhausted conventional treatments, Phase I clinical trials offer the last, best hope: tomorrow's drugs today.Your generous contribution will go directly to the Phase I Team to ensure patients continue to have access to the novel therapies that may increase their quality of life and give them more precious time with their loved ones. Donate Now

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