Azeddine Atfi, Ph.D., has joined Karmanos as the new deputy center director of Research and a tenured professor of research at Wayne State University. With over 25 years in research education, Dr. Atfi’s research interests are uncovering the molecular mechanisms that drive pancreatic ductal adenocarcinoma and its association with cachexia. He has dedicated his career to investigating the processes underlying tumor pathogenesis and progression. Throughout his career, Dr. Atfi has held several prominent leadership roles in research and academic medicine.
His leadership in research began in 2002, when he served as chair of the Cell Signaling Unit at INSERM in Paris, France. This is where he advanced cutting-edge studies on cancer signaling networks. Between 2008 and 2011, he was a faculty member at both Harvard Medical School and the Harvard School of Dental Medicine, where he supported departmental leadership in strategic initiatives and program development. In 2011, he established the Tumor Cell Biology Program at the University of Mississippi Medical Center, serving as the founding director and defining its research mission from the beginning.
In 2018, Dr. Atfi joined Virginia Commonwealth University and its National Cancer Institute (NCI)-designated Massey Cancer Center, where he initially served as chair of Cellular and Molecular Pathogenesis and later as the founding leader of the Cancer Biology Program. His leadership contributed to Massey Cancer Center achieving NCI Comprehensive Designation in 2022.
“With a career distinguished by scientific expertise, visionary leadership, and a proven ability to build collaborative research enterprises, Dr. Atfi is exceptionally positioned to guide innovative cancer research initiatives from conception to impactful outcomes,” said Boris Pasche, M.D., Ph.D., FACP, president and CEO at Karmanos. “Since coming to Karmanos, he has been a champion for our research team members and all their individual contributions to discovering breakthroughs in cancer research. His prior appointments and experience bring the tools Karmanos needs to continue to grow cancer research endeavors in Detroit.”
Dr. Atfi received his Bachelor of Science, Master of Science, and Doctor of Philosophy, all in molecular cellular biology, from the University of Rennes in France. He additionally completed two postdoctoral fellowships: one at McGill University in Montreal, Canada, and the other at Saint-Antoine Hospital in Paris, France.