Having a large clinical trial portfolio means giving patients treatment options often not available anywhere else, and years before they become the standard of care. To learn more about Karmanos Cancer Institute clinical trials or to see if a trial is right for you, please call 1-800-KARMANOS (1-800-527-6266) or request an appointment below
  • A Phase 2, Multicenter Study to Evaluate the Efficacy and Safety Using Autologous Tumor Infiltrating Lymphocytes (LN-145) in Patients with Recurrent, Metastatic or Persistent Cervical Carcinoma

    Cancer Categories
    • Gynecologic
    Karmanos Trial ID
    • 2017-010
    NCT ID
    • NCT03108495
    Age Group
    • Adult
    Scope
    • National
    PhaseClick for Clinical Trial Phase DefinitionPhase II
    Includes controlled clinical studies conducted to evaluate the effectiveness of the drug for a particular indication or indications in participants with the disease or condition under study and to determine the common short-term side effects and risks.
    • Phase II
    Principal Investigator
    • Robert
      Morris, M.D.

      Oncology - Gynecologic, Oncology - Surgical View Profile

    Objective:

    Primary:
    To evaluate the efficacy of LN-145 in patients with recurrent, metastatic, or persistent cervical carcinoma using the objective response rate (ORR).
    Secondary:
    1. To characterize the safety profile of LN-145 in patients with recurrent, metastatic, or persistent cervical carcinoma.
    2. To evaluate efficacy parameters of LN-145 in patients with recurrent, metastatic, or persistent cervical carcinoma such as complete response (CR) rate, duration of response (DOR), disease control rate (DCR), progression-free survival (PFS), and overall survival (OS).
  • Locations

    Locations

    Karmanos Cancer Institute - Detroit Headquarters

    4100 John R
    Detroit, MI 48201
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    Phone: 800-527-6266

    Karmanos Cancer Institute at Lawrence and Idell Weisberg Cancer Treatment Center - Farmington Hills

    31995 Northwestern Hwy
    Farmington Hills, MI 48334
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    Phone: 800-527-6266