Research at Karmanos Cancer Institute

As a leader in cancer research, Karmanos is able to offer patients access to innovative treatments and clinical trials that are not available anywhere else. More than $60 million is invested each year into cancer research with a level of commitment and expertise that cannot be duplicated at community hospitals. 

Maximally Effective Treatment

We believe that our total focus on cancer ensures we will always be the best in developing and applying maximally effective treatment options. Our energy and resources are never diverted to other pursuits.

Learn more about research at Karmanos

    Types of Research

    A cornerstone of the Institute's cancer investigations, tracing its roots back to the establishment of the Detroit Institute for Cancer Research in 1943. Achievements include establishing the first immortal hormone dependent breast cancer cell line, MCF-7, and establishment of premalignant cell line MCF-10; and synthesis of AZT, ddC and d4T, the first FDA-approved treatments for AIDS.

    Clinical research

    Conducted through more than 800 clinical trials at the Institute, including one of the country's leading Phase I programs. Studies are institutional (designed/led by our own investigators), cooperative (with such groups as the Southwest Oncology Group), and pharmaceutical/industry trials. Achievements include establishing the international, nonsurgical standard therapy for anal and esophageal cancers and the concept of the multidisciplinary team, organ preservation and adjuvant chemotherapy.

    Population Research

    • Epidemiological research - Provides a quantitative portrait of cancer and its determinants in a defined population. Core functions are measurement of cancer incidence, morbidity, survival, and mortality. This also includes assessing of genetic predisposition, environmental and behavioral risk factors, screening practices, and the quality of care: from prevention through rehabilitation or hospice.
    • Behavioral research - Investigates whether racial and ethnic attitudes and biases, and real or perceived cultural differences among minority group patients impede effective communication and decision-making in doctor-patient interactions. 

    Karmanos Grand Rounds

    The principal objective of the Karmanos Grand Rounds is to update cancer researchers and physicians on recent advances in the prevention, detection and treatment of cancer.

    View upcoming presentations

The Latest From Karmanos Cancer Institute

News

Karmanos Cancer Center receives overall 5-star rating on Medicare’s Care Compare website

Karmanos Cancer Center in Detroit now has a five-star overall rating, the highest rating possible, from the Centers of Medicare & Medicaid Ser...

Read More

McLaren Health Care and Karmanos Cancer Institute CEOs listed on DBusiness Magazine’s “Detroit 500” for the second consecutive year

Congratulations are again in order for McLaren Health Care president and CEO Philip A. Incarnati and Dr. Gerold Bepler, president and CEO of Barba...

Read More

Dr. Elisabeth Heath discusses liquid biopsies for genitourinary cancers

Caris Molecular Minute Podcast Elisabeth Heath, M.D., FACP,  medical oncologist, leader of the  Genitourinary Oncology Multidisciplinary...

Read More
News

How a preemptive cancer screening helped save this doctor’s life

Listen Now

Eliminating health disparities around multiple myeloma

Listen Now

ACS CAN Michigan Candid Connection

Listen Now