Research at Karmanos Cancer Institute

As a leader in cancer research, Karmanos is able to offer patients access to innovative treatments and clinical trials that are not available anywhere else. More than $60 million is invested each year into cancer research with a level of commitment and expertise that cannot be duplicated at community hospitals. 

Maximally Effective Treatment

We believe that our total focus on cancer ensures we will always be the best in developing and applying maximally effective treatment options. Our energy and resources are never diverted to other pursuits.

Learn more about research at Karmanos

    Types of Research

    A cornerstone of the Institute's cancer investigations, tracing its roots back to the establishment of the Detroit Institute for Cancer Research in 1943. Achievements include establishing the first immortal hormone dependent breast cancer cell line, MCF-7, and establishment of premalignant cell line MCF-10; and synthesis of AZT, ddC and d4T, the first FDA-approved treatments for AIDS.

    Clinical research

    Conducted through more than 800 clinical trials at the Institute, including one of the country's leading Phase I programs. Studies are institutional (designed/led by our own investigators), cooperative (with such groups as the Southwest Oncology Group), and pharmaceutical/industry trials. Achievements include establishing the international, nonsurgical standard therapy for anal and esophageal cancers and the concept of the multidisciplinary team, organ preservation and adjuvant chemotherapy.

    Population Research

    • Epidemiological research - Provides a quantitative portrait of cancer and its determinants in a defined population. Core functions are measurement of cancer incidence, morbidity, survival, and mortality. This also includes assessing of genetic predisposition, environmental and behavioral risk factors, screening practices, and the quality of care: from prevention through rehabilitation or hospice.
    • Behavioral research - Investigates whether racial and ethnic attitudes and biases, and real or perceived cultural differences among minority group patients impede effective communication and decision-making in doctor-patient interactions. 

    Karmanos Grand Rounds

    The principal objective of the Karmanos Grand Rounds is to update cancer researchers and physicians on recent advances in the prevention, detection and treatment of cancer.

    View upcoming presentations

The Latest From Karmanos Cancer Institute

News

Detroit Tigers and Karmanos Cancer Institute bring fans and community together to raise awareness for breast health at Pink out the Park, July 21, 2021

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KSP Specialty Pharmacy is pleased to announce that it has achieved accreditation through the Accreditation Commission for Health Care (ACHC) for i...

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Karmanos Cancer Action Council works to support LGBTQ caregivers

Being a caregiver to a loved one with cancer is a challenging but essential position for anyone who fills it. There is a robust network of resourc...

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News

Karmanos Cancer Institute partners with The Toledo Clinic to establish a new cancer center in Northwest Ohio

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Karmanos President & CEO Dr. Gerold Bepler on Becker’s Healthcare Podcast

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