Having a large clinical trial portfolio means giving patients treatment options often not available anywhere else, and years before they become the standard of care. To learn more about Karmanos Cancer Institute clinical trials or to see if a trial is right for you, please call 1-800-KARMANOS (1-800-527-6266) or request an appointment below
  • A Prospective Comparative Study of Outcomes with Proton and Photon Radiation in Prostate Cancer (COMPPARE)

    Cancer Categories
    • Genitourinary (GU)
    Karmanos Trial ID
    • 2019-012
    NCT ID
    • NCT03561220
    Age Group
    • Adult
    Scope
    • National
    PhaseClick for Clinical Trial Phase DefinitionPhase Not Applicable
    Trials without phases (for example, studies of devices or behavioral interventions)
    • NA
    Principal Investigator

    Objective:

    Primary Objective:
    • To determine if prostate cancer patients treated with proton therapy as compared to IMRT experience improved QOL (bowel urgency and/or bowel frequency as measured by the validated EPIC instrument.
    Secondary Objectives:
    • Determine if prostate cancer patients treated with proton therapy as compared to IMRT experience reduced toxicity [physician-reported (using CTCAE v5) and patient-reported (PRO-CTCAE)]
    • Determine if prostate cancer patients treated with proton therapy as compared to IMRT experience non-inferior or even superior cancer control (recurrence defined per standard definitions).
    • Determine if hypofractionated proton therapy is non-inferior to standard fractionated proton therapy in patient-reported outcomes and physician-reported toxicity.
  • Locations

    Locations

    Karmanos Cancer Institute at McLaren Bay Region

    3140 W Campus Dr.
    Bay City, MI 48706
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    Phone: 989-667-2370

    Karmanos Cancer Institute at McLaren Central Michigan, Morey Cancer Center

    1221 South Drive
    Mt Pleasant, MI 48858
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    Phone: 989-772-6811

    Karmanos Cancer Institute at McLaren Clarkston

    5680 Bow Pointe Dr
    Clarkston, MI 48346
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    Phone: 248-922-6650

    Karmanos Cancer Institute at McLaren Flint

    4100 Beecher Rd
    Flint, MI 48532
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    Phone: 810-342-3800

    Karmanos Cancer Institute at McLaren Greater Lansing

    3520 Forest Rd.
    Lansing, MI 48910
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    Phone: 517-975-9500

    Karmanos Cancer Institute at McLaren Lapeer Region

    1295 Barry Drive
    Lapeer, MI 48446
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    Phone: 800-527-6266

    Karmanos Cancer Institute at McLaren Macomb

    1080 Harrington Blvd
    Mount Clemens, MI 48043
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    Phone: 586-493-7500

    Karmanos Cancer Institute at McLaren Northern Michigan, Petoskey

    560 W Mitchell St
    Petoskey, MI 49770
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    Phone: 231-487-3390

    Karmanos Cancer Institute at McLaren Port Huron

    1221 Pine Grove Ave
    Port Huron, MI 48060
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    Phone: 810-982-5200

    KCI at McLaren Flint - Owosso

    4100 Beecher Road
    Flint, MI 48532
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