Having a large clinical trial portfolio means giving patients treatment options often not available anywhere else, and years before they become the standard of care. To learn more about Karmanos Cancer Institute clinical trials or to see if a trial is right for you, please call 1-800-KARMANOS (1-800-527-6266) or request an appointment below
  • MyDRUG: Myeloma-Developing Regimens Using Genomics (Genomics Guided Multi-arm Trial of Targeted Agents Alone or in Combination with a Backbone Regimen)

    Cancer Categories
    • Hematologic (Blood Cancers)
    Karmanos Trial ID
    • 2018-176
    NCT ID
    • NCT03732703
    Age Group
    • Adult
    • National
    PhaseClick for Clinical Trial Phase DefinitionPhase I
    Includes initial studies to determine the metabolism and pharmacologic actions of drugs in humans, the side effects associated with increasing doses, and to gain early evidence of effectiveness; may include healthy participants and/or patients.
    • Phase I/II
    Principal Investigator
    • Jeffrey
      Zonder, M.D.

      Oncology - Hematology, Oncology - Medical View Profile


    • To evaluate the ORR with targeted agents (TA's) used in combination with backbone regimen (IPd) in patients with an actionable genetic alteration (as per International Myeloma Working Group [IMWG] consensus criteria).
    • To evaluate the ORR with agents used in combination with backbone (or IPd) regimen in patients with no actionable genetic alteration (as per IMWG consensus criteria).
    • To assess AEs, progression-free survival, and OS of functionally high-risk patients treated with TA's or an immunotherapy agent (checkpoint immunotherapy agents will not be used) when used in combination with the respective backbone regimens (IPd).
  • Locations


    Karmanos Cancer Institute - Detroit Headquarters

    4100 John R
    Detroit, MI 48201
    Get Directions
    Phone: 800-527-6266

    Karmanos Cancer Institute at Lawrence and Idell Weisberg Cancer Treatment Center - Farmington Hills

    31995 Northwestern Hwy
    Farmington Hills, MI 48334
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    Phone: 800-527-6266