Having a large clinical trial portfolio means giving patients treatment options often not available anywhere else, and years before they become the standard of care. To learn more about Karmanos Cancer Institute clinical trials or to see if a trial is right for you, please call 1-800-KARMANOS (1-800-527-6266) or request an appointment below
  • A Phase 2, Multicenter, Single-arm Study of Retreatment with Brentuximab Vedotin in Subjects with Relapsed or Refractory Classical Hodgkin Lymphoma (cHL) or CD30-Expressing Peripheral T Cell Lymphoma (PTCL)

    Cancer Categories
    • Hematologic (Blood Cancers)
    Karmanos Trial ID
    • 2019-074
    NCT ID
    • NCT03947255
    Age Group
    • Adult
    • National
    PhaseClick for Clinical Trial Phase DefinitionPhase II
    Includes controlled clinical studies conducted to evaluate the effectiveness of the drug for a particular indication or indications in participants with the disease or condition under study and to determine the common short-term side effects and risks.
    • Phase II
    Principal Investigator
    • Dahlia
      Sano, M.D.

      Oncology - Hematology, Oncology - Medical View Profile


    Primary Objective(s):
    • To assess the antitumor response by BICR of brentuximab vedotin retreatment
    • To assess the safety of retreatment with brentuximab vedotin
    Secondary Objective(s):
    • To assess duration of tumor control, including duration of response (DOR) per BICR
    • To assess progression-free survival (PFS) per BICR
    • To assess overall survival (OS)
    • To assess complete response (CR) rate per BICR
    • To assess the antitumor response per investigator of brentuximab vedotin retreatment
    • To assess DOR rate per investigator assessment
    • To assess PFS per investigator assessment
    • To assess CR rate per inverstigator assessment
  • Locations


    Karmanos Cancer Institute - Detroit Headquarters

    4100 John R
    Detroit, MI 48201
    Get Directions
    Phone: 800-527-6266

    Karmanos Cancer Institute at Lawrence and Idell Weisberg Cancer Treatment Center - Farmington Hills

    31995 Northwestern Hwy
    Farmington Hills, MI 48334
    Get Directions
    Phone: 800-527-6266