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As a leader in cancer research, Karmanos is able to offer patients access to innovative treatments and clinical trials that are often times not available anywhere else.
To offer hope and longer life to patients with all types of cancer, Karmanos offers the latest types of therapy through our clinical trials program. Through clinical trials, we are creating new knowledge about how therapies fight cancer and provide national leadership in testing these new therapies.
We understand that cancer is a complex disease that demands complex care. We provide each patient with a dynamic, carefully constructed treatment plan focused on their specific cancer and their unique needs.
We listen to you to design a plan that provides you with respect, compassionate care and is responsive to your emotional and practical concerns.
Dr. Jose Maciel Larios completed a postdoctoral fellowship in a breast oncology/pharmacology lab at the University of Michigan. During his fellowship, Dr. Larios investigated molecular mechanisms of endocrine resistance in hormone receptor-positive breast cancer. He recapitulated newly published mutations in the estrogen receptor gene using breast cancer cell lines as pre-clinical models. Additionally, Dr. Larios also examined mechanisms of resistance to CDK4/6 inhibitors. He is a member of the American Society of Hematology and the American Society of Clinical Oncology. As a transplant hematologist, he would like to explore the role of the bone marrow microenvironment in leukemia progression.
Research and Clinical Interests:
Patient Power Adult patients with relapsed or refractory large B-cell lymphoma now have access to the FDA-approved drug, brentuximab vedotin (BV). This new approval has extended the use of BV with lenalidomide and rituximab for patients who have had two or more lines of therapy and are ineligible for transplantation. José Larios, M.D. , transplant hematologist and member of the Bone Marrow and Stem Cell Transplant and Hematology Oncology Multidisciplinary Teams at Karmanos, expla...
Latinos en Michigan The Barbara Ann Karmanos Cancer Institute welcomes José Larios, M.D. , transplant hematologist and member of the Bone Marrow and Stem Cell Transplant and Hematology Oncology Multidisciplinary Teams, to its team of oncology experts. Dr. Larios specializes in treating leukemia and lymphoma blood cancers, including Hodgkin and non-Hodgkin lymphomas. Read the article in Spanish here .
The Barbara Ann Karmanos Cancer Institute welcomes José Larios, M.D. , transplant hematologist. Dr. Larios is a member of the Bone Marrow and Stem Cell Transplant and Hematology Oncology Multidisciplinary Teams at Karmanos. He specializes in treating leukemia and lymphoma blood cancers, including Hodgkin and non-Hodgkin lymphomas. He began seeing patients at the Karmanos Cancer Center in Detroit in August 2024. "Karmanos Cancer Institute is an NCI (National Cancer Institute)-Designated Comprehensive Can...