Population Studies Research Program

Mission

The Population Studies Research Program (PS Research Program) is committed to identifying key genetic and behavioral risk factors underlying disease onset and progression, and developing and testing novel intervention strategies to reduce risk and improve diagnosis, treatment and outcomes with an emphasis on reducing and/or eliminating cancer health disparities among populations contained within our catchment area.

Scientific Themes

The PS Research Program themes encompass research to reduce and eliminate disparities across the cancer experience of adult and pediatric populations, and include a diversity of race/ethnic groups. 

• Investigate the distribution and determinants of cancer and cancer risk, survivorship and outcomes in a unique and large underserved population.
• Develop and test interventions focused on patients, family members, physician behaviors and system-level drivers to reduce health disparities in cancer prevention, treatment, survivorship, and end-of-life outcomes.

Program Activities

Members of the Population Studies Research Program regularly interact in several ways to develop scientific directions and implement strategic planning efforts including:

• A PS Research Program Committee meets monthly to discuss strategic directions, research collaborations, plan seminars and retreats, and address general programmatic issues as they arise
• Monthly faculty meetings to discuss epidemiological and communication/behavioral research in progress
• Monthly PS Research Program research meetings and seminar presentations directed at the entire program membership
• Yearly thematic research retreats are held with distinguished national speakers invited to give keynote addresses and faculty and post doctoral fellows presenting their latest research findings
• Karmanos-wide annual scientific retreat
• PS Research Program members are engaged in several Karmanos Research Groups to develop program projects applications.
• A major effort underway is the PS Research Program Survivorship Working Group, this team is conducting a pilot cohort study of Karmanos-based African American and white cancer cases and family members to provide preliminary data for a planned P01, to be submitted in 2015
• Members participate in the Karmanos Lung Cancer Research Group, the Lung Cancer SPORE planning group, the Breast Cancer Research Group and the Prostate Cancer Research Group

Surveillance, Epidemiology, and End Results Program (SEER)

The metropolitan Detroit area is home to a highly diverse and medically underserved population. As part of the original SEER program of nine registries dating back to 1973, we contribute approximately 38% of the national cancer incidence and survival data for African Americans. The SEER registry is not only used for descriptive studies; it provides a population-based source of cases for case-control and case-case comparisons. There are ~25,000 new cancers diagnosed in Metropolitan Detroit each year, with about 25% of those being diagnosed in African Americans. In addition to the large African American population, this area is home to the largest concentration of Arab Americans in the United States. This population diversity provides a remarkable opportunity for the study of race/ethnicity related health disparities. All of the research described is conducted in this context and includes substantial numbers of minorities.